C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/10 (2006.01) C12N 1/20 (2006.01) C12N 1/21 (2006.01) C12N 15/00 (2006.01) C12P 21/06 (2006.01) C12Q 1/02 (2006.01) G01N 33/483 (2006.01) G01N 33/542 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2375708
Recombinant cells expressing fluorescence resonance energy transfer reporter polypeptides and cell-based for apoptosis; screening assays for identifying and selecting candidate compounds modulating apoptosis.
L'invention concerne des cellules recombinées qui expriment des polypeptides rapporteurs à fluorescence de résonance à transfert d'énergie. L'invention concerne également des tests cellulaires de l'apoptose . Cette invention concerne enfin des essais de criblage permettant d'identifier et de sélectionner des composés potentiellement aptes à moduler l'apoptose.
Corey-Naeve Janis
Dyer Rebecca J.
Elliott Kathryn J.
Jones Jay M.
Kounnas Maria Z.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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