Azabiphenylaminobenzoic acid derivatives as dhodh inhibitors

Details Azabiphenylaminobenzoic acid derivatives as dhodh inhibitors Azabiphenylaminobenzoic acid derivatives as dhodh inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/74 (2006.01) A61K 31/44 (2006.01) A61K 31/506 (2006.01) A61P 17/00 (2006.01) A61P 19/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07D 239/42 (2006.01) C07D 401/04 (2006.01) C07D 401/10 (2006.01) C07D 413/10 (2006.01)

Patent

CA 2695475

New azabiphenylaminobenzoic acid derivatives having the chemcial structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of the dehydroorotate dihydrogenase (DHODH).

L'invention porte sur de nouveaux dérivés d'acide azabiphénylaminobenzoïque ayant la structure chimique représentée par la formule (I). L'invention porte également sur un procédé permettant de les préparer, sur des compositions pharmaceutiques les comprenant et sur leur utilisation en thérapie comme inhibiteurs de la dihydroorotate déshydrogénase (DHODH).

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