Azacyclyl-substituted aryldihydroisoquinolinones, process...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/10 (2006.01) A61K 31/4355 (2006.01) A61K 31/4365 (2006.01) A61K 31/4725 (2006.01) A61P 3/10 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 487/10 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01) C07D 498/10 (2006.01)

Patent

CA 2636873

The invention relates to azacyclyl-substituted aryldihydroisoquinolinones and their derivatives, and their physiologically tolerated salts and physiologically functional derivatives, their preparation, medicaments comprising at least one azacyclyl-substituted aryldihydroisoquinolinone of the invention or its derivative, and the use of the azacyclyl-substituted aryldihydroisoquinolinones of the invention and their derivatives as MCH antagonists.

L'invention concerne des aryldihydroisoquinolinones à substitution azacyclyle et leurs dérivés ainsi que leurs sels physiologiquement tolérés et leurs dérivés physiologiquement fonctionnels, leur préparation, des médicaments comprenant au moins une aryldihydroisoquinolinone à substitution azacyclyle de l'invention ou un de ses dérivés, ainsi que l'utilisation des aryldihydroisoquinolinones à substitution azacyclyle de l'invention et de leurs dérivés comme antagonistes de l'hormone de mélanoconcentration (MCH).

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