Azaindole inhibitors of aurora kinases

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2634787

The present invention relates to a compound represented by Formula (I): and pharmaceutically acceptable salts. Compounds of the present invention inhibit Aurora kinase, making them especially suitable for the treatment of a number of diseases, including solid tumor cancers and hematological cancers.

La présente invention concerne un composé représenté par la formule (I) : et ses sels pharmaceutiquement acceptables. Les composés de la présente invention inhibent les kinases Aurora et constituent donc des agents particulièrement adéquats pour traiter un certain nombre de maladies, parmi lesquelles les cancers à tumeurs solides et les cancers hématologiques.

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