C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/245, 167/246
C07D 307/83 (2006.01) A61K 31/655 (2006.01) C07C 107/06 (1985.01)
Patent
CA 1256102
ABSTRACT A compound having an inhibitory effect on 15-hydroxy- prostaglandin dehydrogenase (PGDH). The compound has the following structure: Image (I) in which X, Y and Z are hydrogen, carboxy or lower alkoxy- carbonyl, one of X, Y and Z always being hydrogen and the others being identical or different groups. The invention also comprises lactones and salts of (I).
496020
Agback Karl H.
Nygren Alf S.
Ab Pharmacia
Ridout & Maybee Llp
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