Azolo triazines and pyrimidines

Details Azolo triazines and pyrimidines Azolo triazines and pyrimidines

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4162 (2006.01) A61K 31/4985 (2006.01) A61K 31/505 (2006.01) A61K 31/519 (2006.01) A61K 31/53 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61P 1/00 (2006.01) A61P 1/04 (2006.01) A61P 3/04 (2006.01) A61P 3/08 (2006.01) A61P 9/00 (2006.01) A61P 13/06 (2006.01) A61P 15/00 (2006.01) A61P 15/08 (2006.01) A61P 19/02 (2006.01) A61P 19/10 (2006.01) A61P 25/00 (2006.01) A61P 25/04 (2006.01) A61P 25/08 (2006.01) A61P 25/18 (2006.01) A61P 25/20 (2006.01) A61P 25/22 (2006.01) A61P

Patent

CA 2259583

Corticotropin releasing factor (CRF) antagonists of formula (I) or (II) and their use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or heart-related diseases and colonic hypersensitivity associated with psychopathological disturbance and stress.

Cette invention concerne des inhibiteurs de facteur de libération de corticotropine, lesquels correspondent à la formule (I) ou (II). Cette invention concerne également l'utilisation de ces inhibiteurs dans le traitement de l'anxiété, de dépressions ainsi que d'autres troubles psychiatriques et neurologiques. Ces inhibiteurs peuvent également être utilisés dans le traitement de maladies immunologiques, cardio-vasculaires ou touchant le coeur, ainsi que dans le traitement de l'hypersensibilité du côlon associée à des problèmes psychopathologiques et au stress.

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