Bacillus anthracis spore specific antobodies

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/12 (2006.01) A61K 39/395 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2566840

The invention relates to spore specific antibodies. Compositions and methods relating to the antibodies are provided along with the hybridomas that produce the antibodies. The antibodies are specific for the spores of B. anthracis relative to the vegetative form of the cells. The antibodies are also specific for the spores relative to other Bacillus spores and cells. The antibodies may be used to detect the presence of B. anthracis spores by use of methods provided herein. The invention also relates to articles of manufacture as well as kits comprising these antibodies which may be used in the detection methods of the invention.

La présente invention concerne, d'une part des anticorps spécifiques de spores, et d'autre part des compositions et procédés se rapportant à ces anticorps, ainsi que les hybridomes qui produisent ces anticorps. Ces anticorps sont spécifiques des spores de B. anthracis par rapport à la forme végétative des cellules. Ces anticorps sont également spécifiques de spores par rapport à d'autres et cellules et spores de Bacillus. Ces anticorps peuvent s'utiliser pour détecter la présence de spores de B. anthracis au moyen de procédés de l'invention. L'invention concerne également des articles manufacturés ainsi que des nécessaires comprenant ces anticorps qui peuvent s'utiliser pour les procédés de détection de l'invention.

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