Bactericidal agents based on quinolonecarboxylic acids

Details Bactericidal agents based on quinolonecarboxylic acids Bactericidal agents based on quinolonecarboxylic acids

C - Chemistry, Metallurgy

07

D

260/266.3, 167/7

C07D 401/00 (2006.01) A01N 43/60 (2006.01) C07D 215/56 (2006.01) C07D 401/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1222249

ABSTRACT Bactericidal agents based on quinolonecarboxylic acids The invention relates to the bactericidal use of new 1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid derivatives of the formula (I) Image (II) ( I I ) in which R1 represents a CO-R6, CN, So2-R7 or S-R3 radical, wherein R6 represents hydrogen, optionally substituted straight chain or branched alkyl with 1 to 6 carbon atoms, optionally substituted aryl with 6 or 10 carbon atoms, optionally substituted aralkyl with 6 carbon atoms in the aryl part and 1 to 3 carbon atoms in the alkyl part, optionally substituted alkoxy or alkyl- thio with 1 to 6 carbon atoms, optionally substituted aryloxy with 6 carbon atoms, optionally substituted benzyloxy, amino, optionally substituted alkylamino or dialkylamino with 1 to 6 carbon atoms per alkyl radical or optionally substituted phenylamino, R7 represents optionally substituted straight- chain or branched alkyl with 1 to 5 carbon atoms, phenyl or methylphenyl and R8 represents methoxycarbonyl, trichloromethyl, trifluoromethyl or dichlorofluoromethyl, R2, R3, R4 and R5 can be identical or different and represent hydrogen, methyl, ethyl or n- or i-propyl and X represents hydrogen, halogen, preferably fluorine or chlorine, or nitro.

449254

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