C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/70 (2006.01) C12N 7/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/04 (2006.01) C12M 1/34 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2665599
A method is disclosed for anchoring a bacteriophage on a substrate, the bacteriophage having a phage amine moiety, the method comprising: producing a free amine terminal moiety on the substrate by chemical modification of the substrate; activating the free amine terminal moiety with a cross-linking agent to produce an active functional group to couple to the phage amine moiety; and anchoring the bacteriophage to the substrate using the active functional group. A sensor is also disclosed comprising: a substrate; an anchor group attached by chemical modification to the substrate and having an active functional group produced by the activation of a free amine terminal moiety; and a bacteriophage having a phage amine moiety coupled to the active functional group to anchor the bacteriophage to the substrate.
Evoy Stephane
Glass Nicholas R.
Singh Amit
Lambert Anthony R.
The Governors Of The University Of Alberta
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