Bax omega protein and methods

Details Bax omega protein and methods Bax omega protein and methods

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07H 21/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2224701

Bax-.omega. polynucleotides and polypeptides, and compositions effective to hybridize to Bax-.omega. polynucleotides are disclosed. Also disclosed are methods for altering apoptosis in cells, for promoting cell survival and for identifying compounds capable of affecting the binding of Bax-.omega. to other proteins involved in apoptosis.

L'invention concerne des polynucléotides et polypeptides Bax-.omega., et des compositions efficaces pour une hybridation avec des polynucléotides Bax-.omega.. Elle se rapporte également à des procédés pour changer l'apoptose dans les cellules, pour promouvoir la survie des cellules et pour identifier des composés capables d'influencer la liaison de Bax-.omega. avec d'autres protéines impliquées dans l'apoptose.

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