Benzamidine derivatives

Details Benzamidine derivatives Benzamidine derivatives

C - Chemistry, Metallurgy

07

C

C07C 257/18 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/34 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/505 (2006.01) C07C 271/22 (2006.01) C07C 279/18 (2006.01) C07C 309/64 (2006.01) C07C 311/06 (2006.01) C07C 311/13 (2006.01) C07C 311/14 (2006.01) C07C 311/15 (2006.01) C07C 311/19 (2006.01) C07C 323/62 (2006.01) C07C 327/48 (2006.01) C07D 207/08 (2006.01) C07D 207/12 (2006.01) C07D 207/325 (2006.01) C07D 207/327 (2006.01) C07D 20

Patent

CA 2278180

Benzamidine derivatives involving compounds represented by formulae (a) and (b) and analogs thereof or pharmaceutically acceptable salts thereof. These compounds show anticoagulant effects based on their excellent effects of inhibiting activated blood coagulation factor X, which makes them useful as an anticoagulant.

L'invention concerne des dérivés de benzamidine qui comportent des composés représentés par les formules (a) et (b), ainsi que leurs analogues ou leurs sels pharmaceutiquement acceptables. Ces composés présentent des effets anticoagulants, dus à leur excellente capacité d'inhibition du facteur de coagulation sanguine X activé; cela permet de les utiliser en tant qu'anticoagulant.

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