C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/26 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) C07D 235/30 (2006.01)
Patent
CA 2321110
A novel benzimidazole derivative [specifically, for example, 2-ethoxy-1-[{4'- (2''-N,N-dimethylamino-ethoxycarbonyl)phenyl}methyl]-1H-benzimidazole-6- carboxylic acid morpholide] represented by formula (I) and a salt thereof. The compound exhibits satisfactory curative and preventive effects for cardiac and nephric diseases, although it has little action to blood-pressure.
Nouveau dérivé du benzimidazole (plus précisément, par exemple, le morpholide de l'acide 2-éthoxy-1-[(4'-(2''-N,N-diméthylamino-éthoxycarbonyl)phényl)méthyl]-1H-benzimidazole-6-carboxylique), représenté par la formule (I), et sel dudit dérivé. Ce composé possède une activité thérapeutique et préventive satisfaisante dans les maladies cardiaques et rénales, bien qu'il ait peu d'effet sur la pression artérielle.
Dewa Toshikazu
Enari Hiroyuki
Ise Michihito
Maruoka Hiroshi
Nishijima Fuyuhiko
Fetherstonhaugh & Co.
Kureha Chemical Industry Co. Ltd.
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