Benzimidazole derivatives and process for their preparations

C - Chemistry – Metallurgy – 07 – C

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260/466.05, 260/

C07C 257/06 (2006.01) C07D 235/04 (2006.01) C07D 235/12 (2006.01) C07D 235/28 (2006.01)

Patent

CA 1318676

S P E C I F I C A T I O N Title of the invention : Benzimidazole derivatives and process for their preparations Abstract of the invention : Benzimidazole derivatives of the following formula, Image wherein R1 indicates hydrogen atom, lower alkyl group having carbon atoms of 1 to 6 or dimethylaminopropyl group, R2 indicates hydrogen atom or lower alkanoyl group having carbon atoms of 1 to 3, R3 indicates hydrogen atom, lower alkyl group having carbon atoms of 1 to 3 or lower alkanoyl group having carbon atoms of 1 to 3, X indicates sulfur atom, sulfinyl group, sulfonyl group, amino group or methylene group, A indicates alkylene group having carbon atoms of 1 to 12, which alkylene group may optionally be substituted by hydroxy group or lower alkyl group having carbon atoms of 1 to 3, -(CHR')n-CR"=CR"-(CHR')m-, -(CHR')n Image (CHR')m- (in which R' and R" are each independently hydrogen atom, lower alkyl group having carbon atoms of 1 to 3 or hydroxy group, and n and m are equal to 0, 1, 2 or 3), and Y indicates oxygen atom or sulfur atom; their acid or alkali salts and hydrate thereof are useful as antiallergic agents.

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