Benzimidazole derivatives which are to be used as antagonist...

Details Benzimidazole derivatives which are to be used as antagonist... Benzimidazole derivatives which are to be used as antagonist...

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/4184 (2006.01) A61K 31/454 (2006.01) A61P 1/00 (2006.01) A61P 9/00 (2006.01) A61P 23/00 (2006.01) A61P 25/16 (2006.01) A61P 25/22 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01) C07D 235/08 (2006.01) C07D 403/06 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2654250

Compounds of formula I or pharmaceutically acceptable salts thereof: wherein X, A, R1, R2, R3 and R4 are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

La présente invention concerne la préparation de composés de formule I ou des sels pharmaceutiquement acceptables de ceux-ci : où X, A, R1, R2, R3 et R4 sont comme défini dans la spécification ainsi que de sels et de compositions pharmaceutiques comprenant les composés. Ceux-ci sont utiles en thérapie, en particulier dans le contrôle de la douleur.

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