Benzodiazepin-2-on derivatives

Details Benzodiazepin-2-on derivatives Benzodiazepin-2-on derivatives

C - Chemistry, Metallurgy

07

D

C07D 243/12 (2006.01) A61K 31/551 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 43/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2749700

The present invention relates to a compound represented by the formula(I): wherein R1 represents a hydrogen atom or the like;R2 represents lower alkyl or the like;R3 and R4 represent lower alkyl or the like;R5 represents phenyl or the like;R6 rep-resents a hydrogen atom or the like;m is an integer of from 0 to 2;p is an integer of from 1 to 4; and q is an integer of from 1 to 5, or a pharmaceutical acceptable saltthereof, and a DGAT 1 inhibitor comprising the compound.

La présente invention concerne un composé de formule (I) : où R1 représente un atome d'hydrogène, etc. ; R2 représente un groupement alkyle court, etc. ; R3 et R4 représentent un alkyle court, etc. ; R5 représente un groupement phényle, etc. ; R6 représente un atome d'hydrogène, etc. ; m est égal à un entier compris entre 0 et 2 ; p est égal à un entier compris entre 1 et 4 ; et q est égal à un entier compris entre 1 et 5, ou l'un de ses sels de qualité pharmaceutique, ainsi qu'un inhibiteur de DGAT 1 comprenant ledit composé.

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