Benzodiazepines, process and intermediates for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/06 (2006.01) A61K 31/55 (2006.01) C07D 487/06 (2006.01)

Patent

CA 1340074

The invention relates to benzodiazepines of formula: (see fig.I) in which R1 is H or halogen, R2 is H or halogen, Ar is indolyl, phenyl, naphthyl, indolyl monosubstituted with a halogen or with a methoxy or phenyl mono-, di- or trisubstituted with a halogen or with a methoxy or with a trifluoromethyl group, and n is 2 or 3; and their optical isomers. The compounds are useful chiefly for combating gastrointestinal disorders and disorders of the pancreas, the gallbladder and the appetite; pain.

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