Benzofuranyl-and benzothienyl-piperazinyl quinolines as...

C - Chemistry – Metallurgy – 07 – D

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C07D 405/14 (2006.01) A61K 31/496 (2006.01) A61P 25/24 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2524324

Benzofuranyl-and benzothienyl-piperzinyl quinoline derivatives and compositions containing such compounds are disclosed. Methods of using benzofuranyl- and benzothienyl-piperzinyl quinoline derivatives and compositions containing such composition in the treatment and/or prevention of serotonin-related disorders, such as depression and anxiety, are also disclosed. In addition, processes for the preparation of benzofuranyl- and benzothienyl-piperzinyl quinoline derivatives are disclosed.

L'invention porte sur des dérivés de quinolines benzofuranyl et benzothiényl-pipérazinyl et sur des compositions contenant ces composés. L'invention porte également sur des procédés d'utilisation des dérivés de quinolines benzofuranyl et benzothiényl-pipérazinyl et des compositions contenant ces composés dans le traitement et/ou la prévention de troubles liés à la sérotonine tels que la dépression et l'anxiété. L'invention porte, de plus, sur des procédés de préparation des dérivés de quinolines benzofuranyl et benzothiényl-pipérazinyl.

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