Benzofuro-1,4-diazepin-2-one derivatives

Details Benzofuro-1,4-diazepin-2-one derivatives Benzofuro-1,4-diazepin-2-one derivatives

C - Chemistry, Metallurgy

07

D

C07D 491/04 (2006.01) A61K 31/551 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2519987

The invention relates to novel benzofuro-1,4-diazepin-2-one derivatives, to a method for producing said derivatives and to their use as P2X4 receptor antagonists for producing medicaments for the treatment and/or prophylaxis of diseases, in particular arteriosclerosis, restenosis and other inflammatory diseases.

La présente invention concerne de nouveaux dérivés de benzofuro-1,4-diazépin-2-one, leur procédé de production et leur utilisation comme antagoniste du récepteur P2X¿4? pour la production de médicaments destinés au traitement et/ou à la prophylaxie de maladies, notamment d'artériosclérose, de resténose et autres maladies inflammatoires.

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