C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/47 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2495225
The invention relates to the discovery of the role of beta-2 microglobulin (B2M) in the pathogenesis of osteoarthritis (OA) and the ability of B2M to inhibit chondrocyte proliferation. The invention further relates to the identification of genes regulated by B2M (the "B2M related genes").
La présente invention traite de la découverte d'une part du rôle joué par la bêta-2 microglobuline (B2M) dans la pathogenèse de l'arthrose (OA) et d'autre part de l'aptitude de la B2M à inhiber la prolifération des chondrocytes. Cette invention concerne également l'identification de gènes régulés par la B2M (appelés "gènes associés à la B2M").
Liew Choong-Chin
Marshall Wayne E.
Zhang Hongwei
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Chondrogene Inc.
Genenews Corporation
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