A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 31/138 (2006.01) A61K 31/165 (2006.01) A61K 31/5377 (2006.01) A61P 19/08 (2006.01) A61P 19/10 (2006.01)
Patent
CA 2566746
The instant invention relates to compositions and methods for treating or preventing bone diseases. In certain aspects, the invention provides compositions comprising a .beta.-adrenergic antagonist or agonist associated to a bone-targeted molecule, as well as methods of modulating bone mass and/or growth in a mammal by administering a composition of the present invention. In other aspects, the invention provides methods of modulating bone mass and/or growth in a mammal by administering a composition comprising a .beta.2- selective antagonist or agonist.
Cette invention concerne des compositions et des procédés pour traiter ou prévenir les maladies osseuses. Dans certains de ses aspects, cette invention concerne des compositions comprenant un antagoniste ou un agoniste .beta.-adrénergique associé à une molécule de ciblage osseux, ainsi que des procédés pour moduler la masse et/ou la croissance osseuse chez un mammifère, en lui administrant une telle composition. Dans d'autres aspects, cette invention concerne des procédés pour moduler la masse et/ou la croissance osseuse chez un mammifère en lui administrant une composition comprenant un antagoniste ou un agoniste .beta.-adrénergique.
Devens Bruce
Karsenty Gerard
Baylor College Of Medicine
Borden Ladner Gervais Llp
LandOfFree
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