.beta.-d-galactose derivatives, a process for their...

Details .beta.-d-galactose derivatives, a process for their... .beta.-d-galactose derivatives, a process for their...

C - Chemistry, Metallurgy

07

H

167/129, 530/13,

C07H 15/04 (2006.01) C07H 3/06 (2006.01) C07K 9/00 (2006.01) G01N 33/531 (2006.01) G01N 33/543 (2006.01) G01N 33/80 (2006.01)

Patent

CA 1268000

- 1 - HOE 82/B 010 Abstract of the disclosure: New compounds of the general formula I Image I in which R1 and R2 each denote a hydrogen atom or an acyl or benzyl protective group, R1 and R2 together denote an alkylidene or benzylidene protective group, R4 denotes a hydrogen atom, an acyl or benzyl protective group or a 2,3,4-tri-0-benzyl-?-L-fucopyranosyl or ?-L-fucopyranosyl radical, R5 denotes H, OH, NH2, NHNH2, N3, O-alkyl, O-aryl, NH-(CH2)mMH2, where m = 2 - 5, lysine, polylysine or a carrier, n denotes a number from 1 to 10 and R3 denotes a hydrogen atom, an acyl or benzyl protective group or an ?-D-glycopyranosyl radical of the general formula II - 2 - Image II in which R6 denotes a hydrogen atom or an acyl or benzyl protective group, R7 denotes a hydrogen atom or halogen and R8 denotes a hydrogen atom, an acyloxy or benzyloxy group or an azido, amino, acetamido or hydroxyl group, a process for their preparation and their use, when bonded to a carrier, as synthetic antigens, glycolipids or immuno-adsorbents, are described.

429113

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