Bicyclic compounds, processes for preparation thereof and...

Details Bicyclic compounds, processes for preparation thereof and... Bicyclic compounds, processes for preparation thereof and...

A - Human Necessities

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A61K 31/47 (2006.01) C07C 45/67 (2006.01) C07C 45/68 (2006.01) C07C 49/747 (2006.01) C07C 49/755 (2006.01) C07D 213/30 (2006.01) C07D 213/63 (2006.01) C07D 215/14 (2006.01) C07D 215/22 (2006.01) C07D 235/12 (2006.01) C07D 277/64 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1314553

A B S T R A C T Bicyclic compounds and pharmaceutically acceptable salts thereof which can be represented by the following general formula: Image wherein A is Image or Image , R1 is aryl which may have cyano or carbamoyl, or heterocyclic group which may have lower alkyl, R2 is hydrogen or lower alkyl, R3 is lower alkyl, X is hydrogen, halogen, hydroxy or lower alkyl, m is an integer 1 or 2, and n is an integer 1 to 4, and pharmaceutically acceptable salts thereof. These compounds and their salts have 5-lipoxygenase- inhibiting activity. Processes for the preparation of these compounds and compositions containing them are also disclosed.

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