C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 473/04 (2006.01) A61K 31/5025 (2006.01) A61K 31/522 (2006.01) A61P 3/10 (2006.01) A61P 5/50 (2006.01) C07D 235/00 (2006.01) C07D 237/00 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2548323
The invention relates to bicyclic imidazole compounds of general formula (I), in which R1 to R3 and A are defined as cited in Claims 1 to 8, and to tautomers, stereoisomers, mixtures and salts thereof that have valuable pharmacological properties, particularly an inhibiting effect upon the activity of the enzyme dipeptidyl peptidase-IV (DPP-IV).
L'invention concerne des composés imidazol bicycliques de formule générale (I), dans laquelle R?1¿ à R?3¿ et A sont tels que définis dans les revendications 1 à 8, ainsi que leurs tautomères, leurs stéréoisomères, leurs mélanges et leurs sels, lesquels présentent des propriétés pharmacologiques précieuses, en particulier un effet inhibiteur sur l'activité de l'enzyme dipeptidylpeptidase-IV (DPP-IV).
Eckhardt Matthias
Hauel Norbert
Himmelsbach Frank
Langkopf Elke
Tadayyon Mohammad
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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