C - Chemistry – Metallurgy – 12 – M
Patent
C - Chemistry, Metallurgy
12
M
C12M 3/02 (2006.01) C12M 1/40 (2006.01)
Patent
CA 2422230
The invention provides a bio-reactor device and a method of cultivating live cells. The device comprises a holder which contains a matrix of porous foam material in whose interior live cells are anchored, the device comprising also a liquid contained in the holder. The liquid is an oxygen carrier and saturates the matrix, the liquid comprising a synthetic or semi-synthetic constituent. The method involves perfusing the oxygen carrier liquid through the matrix to deliver oxygen to the cells and to absorb carbo-dioxide from the cells.
La présente invention concerne un dispositif bioréacteur et un procédé permettant la culture de cellules vivantes. Le dispositif comprend un élément de réception qui contient une matrice de matière en mousse poreuse à l'intérieur de laquelle sont ancrées des cellules vivantes, ledit dispositif comprenant également un liquide contenu dans l'élément de réception. Le liquide est un agent de transport d'oxygène et sert à saturer la matrice, ledit liquide comprenant un constituant synthétique ou semi-synthétique. Le procédé fait intervenir le passage du liquide de transport d'oxygène à travers la matrice afin de fournir de l'oxygène aux cellules et d'absorber le dioxyde de carbone qu'elles rejettent.
Bond Robert Paul
Moolman Francis Sean
Van Der Merwe Schalk
Van Wyk Adriaan Jacobus
Csir
Sim & Mcburney
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