Bioactive glass compositions and methods of treatment using...

C - Chemistry – Metallurgy – 03 – C

Patent

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C03C 3/097 (2006.01) A61K 6/027 (2006.01) A61K 6/06 (2006.01) A61K 8/22 (2006.01) A61K 8/25 (2006.01) A61Q 11/00 (2006.01) C03C 3/078 (2006.01) C03C 3/11 (2006.01) C03C 4/00 (2006.01) C03C 12/00 (2006.01)

Patent

CA 2244722

A novel silica-based bioactive glass composition that can be used in conjunction with a delivery agent such as a toothpaste, gel, etc., having a particle size range < 90 µm which will form a rapid and continuous reaction with body fluids due to the immediate and long-term ionic release of Ca and P from the core silica particles, to produce a stable crystalline hydroxy carbonate apatite layer deposited onto and into the dentin tubules for the immediate and long-term reduction of dentin hypersensitivity and tooth surface remineralization.

L'invention concerne une nouvelle composition de verre bioacif à base de silice qui peut être utilisée en association avec un agent vecteur tel qu'une pâte dentifrice, un gel, etc. Cette composition a une granulométrie < 90 mu m et elle entre en réaction d'une manière rapide et continue avec les liquides biologiques en assurant une libération ionique immédiate et a long terme de Ca et de P à partir des particules du noyau en silice, pour former une couche d'hydroxycarbonate-apatite cristalline stable, déposée sur et dans les tubules de la dentine, ce qui a pour effet de diminuer immédiatement et à long terme l'hypersensibilité de la dentine et d'assurer la reminéralisation de la surface des dents.

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