Biodegradable multi-block co-polymers

Details Biodegradable multi-block co-polymers Biodegradable multi-block co-polymers

C - Chemistry, Metallurgy

08

G

C08G 63/664 (2006.01) A61K 47/34 (2006.01) C08G 18/08 (2006.01) C08G 18/42 (2006.01) C08G 63/08 (2006.01) C08G 63/78 (2006.01)

Patent

CA 2553619

The invention relates to a biodegradable multi-block copolymer, comprising at least two hydrolysable segments derived from pre-polymers A and B, which segments are linked by a multi-functional chain-extender and are chosen from the pre-polymers A and B, and triblock copolymers ABA and BAB, wherein the multi-block copolymer is amorphous at physiological (body) conditions. The invention further relates to a process for preparing said copolymer and to its use as a medical implant, a coating for a medical device or a drug delivery vehicle.

L'invention concerne un copolymère biodégradable multiblocs comprenant au moins deux segments hydrolysables dérivés des pré-polymères A et B, ces segments étant liés au moyen d'un allongeur de chaîne multi-fonctionnel et étant choisis parmi les pré-polymères A et B, ainsi que des copolymères triblocs ABA et BAB, le copolymère multiblocs étant amorphe dans des conditions physiologiques (corps). L'invention concerne également un procédé de préparation du copolymère et l'utilisation de celui-ci comme implant médical, revêtement destiné à un dispositif médical ou véhicule d'administration de médicament.

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