Biologically active composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 9/08 (2006.01) A61K 9/14 (2006.01) A61K 9/70 (2006.01) A61K 47/14 (2006.01)

Patent

CA 2331527

The invention relates to a novel biologically active composition which comprises a biologically active agent to be released therefrom, said biologically active agent being dissolved and/or dispersed in a supersaturated state within a carrier, which carrier comprises a liquid and/or solid non-crystalline ester and/or polyester matrix, and where the precipitation of said biologically active agent is substantially, or completely, inhibited therein. Said supersaturated state is obtainable by subjecting one or more carrier starting substance(s) to such chemical reaction(s) that an ester and/or polyester matrix is provided, the biologically active agent being added after said chemical reaction(s) has (have) been completed.

L'invention concerne une nouvelle composition biologiquement active dont on peut extraire un agent biologiquement actif. Cet agent biologiquement actif est dissout et/ou dispersé dans un état sursaturé à l'intérieur d'un support contenant une matrice ester et/ou polyester non cristalline liquide et/ou solide. La précipitation dudit agent biologiquement actif y est sensiblement ou complètement inhibée. On obtient cet état sursaturé en soumettant un ou plusieurs excipients d'amorçage à une (des) réaction(s) chimique(s) pouvant produire une matrice ester et/ou polyester, l'agent biologiquement actif étant ajouté à l'issue de la (des) réaction(s).

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