Biosensor and interface membrane

Details Biosensor and interface membrane Biosensor and interface membrane

B - Operations, Transporting

01

D

B01D 71/68 (2006.01) B01D 67/00 (2006.01) C12M 1/40 (2006.01) C12Q 1/00 (2006.01) G01N 27/327 (2006.01)

Patent

CA 2132569

A regenerable biosensor probe adapted for positioning in a bioreactor comprises a selectively permeable interface membrane, a porous protein-receiving matrix adjacent to the interface membrane, an indicating electrode, an inlet conduit through which fresh protein conjugate may flow to the protein-receiving matrix, and an outlet conduit through which spent protein conjugate may be removed from the protein-receiving matrix. A selectively permeable interface membrane, which may be used in a biosensor system to separate biochemical, optical or other processes from an analyte matrix comprises a supporting mesh, a perfluorosulfonic acid polymer impregnated substrate and a homogenous film of perfluorosulfonic acid polymer. A method of preparing this interface membrane comprises fixing a substrate on to a supporting mesh to form a substrate membrane, casting a perfluorosulfonic acid polymer on the substrate membrane and curing the product to so formed.

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