Blood vessel lipid deposition-preventive agent comprising...

Details Blood vessel lipid deposition-preventive agent comprising... Blood vessel lipid deposition-preventive agent comprising...

A - Human Necessities

61

K

A61K 31/517 (2006.01) A61K 45/00 (2006.01) A61P 9/10 (2006.01) C07D 239/96 (2006.01) C07D 401/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2358314

Preventive or therapeutic agents for diseases accompanied with vascular function disorders related to deposition of lipid on vessel walls, containing specific chymase inhibitors as the active ingredient. Quinazoline derivatives of general formula (1) are usable as the specific chymase inhibitor. In said formula, A is an aromatic ring.

L'invention concerne des agents thérapeutiques ou préventifs contre des maladies accompagnées de troubles de la fonction vasculaire, relatifs au dépôts de lipides sur les parois des vaisseaux, contenant comme principe actif des inhibiteurs de chymase spécifiques. Des dérivés quinazolinéiques de formule générale (1) peuvent être utilisés en tant qu'inhibiteurs de chymase spécifiques. Dans la formule (1), A représente un cycle aromatique.

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