Bone augmentation utilizing muscle-derived progenitor...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 35/32 (2006.01) A61K 35/38 (2006.01) A61P 19/00 (2006.01) A61P 19/10 (2006.01)

Patent

CA 2734858

The present invention provides muscle-derived progenitor cells that show long- term survival following transplantation into body tissues and which can augment non-soft tissue following introduction (e.g via injection, transplantation, or implantation) into a site of non- soft tissue (e g. bone) when combined with a biocompatible matrix, preferably SIS The invention further provides methods of using compositions comprising muscle-derived progenitor cells with a biocompatible matrix for the augmentation and bulking of mammalian, including human, bone tissues m the treatment of various functional conditions, including osteoporosis, Paget's Disease, osteogenesis imperfecta, bone fracture, osteomalacia, decrease in bone trabecular strength, decrease in bone cortical strength and decrease in bone density with old age.

La présente invention concerne des cellules progénitrices dérivées du muscle qui présentent une survie à long terme après transplantation dans des tissus corporels et qui peuvent augmenter un tissu non mou après introduction (par exemple par injection, transplantation, ou implantation) dans un site de tissu non mou (par exemple, os) lorsqu'elles sont combinées avec une matrice  biocompatible, de préférence SIS. L'invention concerne en outre des procédés d'utilisation des compositions comprenant des  cellules progénitrices dérivées du muscle avec une matrice biocompatible pour l'augmentation et l'accroissement du volume de tissus osseux de mammifères, y compris l'homme dans le traitement de divers états fonctionnels, notamment l'ostéoporose, la maladie de Paget, l'ostéogénèse imparfaite, la fracture osseuse, l'ostéomalacie, la réduction de la résistance trabéculaire de l'os, la diminution de la résistance corticale de l'os et la diminution de la densité osseuse liée au vieillissement.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Bone augmentation utilizing muscle-derived progenitor... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bone augmentation utilizing muscle-derived progenitor..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bone augmentation utilizing muscle-derived progenitor... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1914715

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.