Bone marrow-derived mesenchymal stem cells as a source of...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/079 (2010.01) C12N 5/077 (2010.01) A61K 35/28 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2668200

Methods are provided for treating and/or reducing the severity of multiple sclerosis in a human, by administering autologous mesenchymal stem cell-derived neural precursors. Also described is an in vitro method for differentiating mesenchymal stem-cell derived neural precursor oligodengroglial and neuronal cell types.

L'invention concerne des procédés de traitement et/ou de réduction de la gravité de la sclérose en plaques chez un humain par administration de précurseurs neuraux dérivés de cellules souches mésenchymateuses autologues. L'invention concerne également un procédé in vitro de différenciation des types de cellules neuronales et oligodengrogliales de précurseurs neuraux dérivés de cellules souches mésenchymateuses.

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