Breath test device and method

A - Human Necessities – 61 – K

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A61K 49/00 (2006.01) A61B 5/08 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2732342

There is provided a method of evaluating a liver condition of a subject, the method includes computing a fluctuation parameter from a liver breath test based on at least one of a percentage dose recovery (PDR) curve and a delta over baseline (DOB) curve of an isotope labeled methacetin, or a salt or a derivative thereof, and evaluating at least one liver condition of the subject, based at least on the fluctuation parameter. There is provided herein a method of evaluating a liver condition of a subject, the method includes computing a hepatic impairment score based at least on a breath test related parameter and on a demographic parameter.

Linvention concerne un procédé d'évaluation de l'état hépatique d'un sujet, qui consiste à calculer un paramètre de fluctuation dans une épreuve respiratoire hépatique basée sur au moins une courbe de récupération de dosage en pourcentage (PDR) ou une courbe delta au-dessus de la ligne de base (DOB) d'une méthacétine marquée par un isotope ou son sel ou dérivé; et à évaluer au moins un état hépatique du sujet sur la base au moins du paramètre de fluctuation. Linvention concerne un procédé d'évaluation de l'état hépatique d'un sujet, qui consiste à calculer un indice de déficience hépatique basé au moins sur un paramètre se rapportant à une épreuve respiratoire et sur un paramètre démographique.

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