C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/58 (2006.01) C07C 233/60 (2006.01) C07C 233/63 (2006.01) C07D 207/09 (2006.01) C07D 211/26 (2006.01) C07D 213/40 (2006.01) C07D 231/12 (2006.01) C07D 233/64 (2006.01) C07D 235/14 (2006.01) C07D 239/30 (2006.01) C07D 249/08 (2006.01) C07D 277/28 (2006.01) C07D 277/62 (2006.01) C07D 307/52 (2006.01) C07D 319/12 (2006.01)
Patent
CA 2760885
The present invention relates to bridged spiro[2.4]heptane derivatives of formula (I), wherein W, Y, Z, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds as ALX receptor and/or FPRL2 agonists for the treatment of inflammatory and obstructive airways diseases.
La présente invention concerne des dérivés de spiro[2.4]heptane pontés de formule (I), dans laquelle W, Y, Z, R1 et R2 sont tels que définis dans la description, leur préparation et leur utilisation en tant que composés pharmaceutiquement actifs comme agonistes du récepteur de ALX et/ou du récepteur FPRL2 pour le traitement des maladies inflammatoires et obstructives des voies respiratoires.
Bur Daniel
Corminboeuf Olivier
Cren Sylvaine
Grisostomi Corinna
Leroy Xavier
Actelion Pharmaceuticals Ltd
Gowling Lafleur Henderson Llp
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