Broad ion fragmentation coverage in mass spectrometry by...

H - Electricity – 01 – J

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H01J 49/42 (2006.01)

Patent

CA 2481777

In the field of mass spectrometry, a method of obtaining a mass spectrum enriched with fragment ions while retaining the precursor ion. The technique includes varying the collision energy experienced by the precursor ion such that a range of fragmentations occur. Related methods are also disclosed for obtaining MS, MS2, MS3 and MSn spectra which are enriched with fragment ions.

Cette invention, relative au domaine de la spectrométrie de masse, a trait à un procédé permettant d'obtenir un spectre de masse, enrichi par des ions fragmentés, tout en retenant l'ion précurseur. Ce procédé consiste à faire fluctuer l'énergie de collision subie par l'ion précurseur afin d'obtenir une gamme donnée de fragmentations. L'invention porte également sur des procédés connexes permettant d'obtenir des spectres MS, MS?2¿, MS?3¿ et MS?n¿, enrichis par? ¿des ions fragmentés.

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