Brush polymer coating by in situ polymerization from...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 239/10 (2006.01) C08G 61/12 (2006.01) C09D 201/00 (2006.01)

Patent

CA 2751242

The invention provides compositions that include crosslinking agents having multiple photoactivatable groups, such as diaryl ketones, or a diaryl ketone, such as benzophenone, and at least one polymerizable monomer, such as a zwitterionic monomer. The compositions are useful as surface coating agents that provide brush type polymeric coatings. These polymeric coatings can be used on medical devices, such as artificial joints, to reduce wear and tear between the components of the joint and thus reduce or eliminate debris generated by friction between the joint components.

La présente invention concerne des compositions comprenant des agents de réticulation comportant de multiples groupes photoactivables, tels que des diarylcétones, ou une diarylcétone, telle que de la benzophénone, et au moins un monomère polymérisable, tel qu'un polymère zwitterionique. Les compositions sont utiles en tant qu'agents de revêtement de surface qui fournissent des revêtements polymères de type à la brosse. Ces revêtements polymères peuvent être utilisés sur des dispositifs médicaux, tels que des prothèses articulaires, afin de réduire l'usure entre les composants de la prothèse, et ainsi réduire ou éliminer les débris générés par frottement entre les composants de prothèse.

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