A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/107 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/34 (2006.01) A61P 7/02 (2006.01)
Patent
CA 2578130
Butylbenzene phthalein Self-emulsifying Drug Delivery System(SEDDS), its preparation method and application. Said SEDDS comprises 1 % - 65 % butylbenzene phthalein and 10 % - 65 % emulsifier as essential constitutents. Said SEDDS can be used for the manufacture of various solid or liquid dosage forms (e.g., tablet, soft/hard capsule and others). The present SEDDS can self- emulsify in the gastrointestinal tract, increasing the contact area between the gastrointestinal tract and the drug, and accordingly improving absorptivity of drug.
La présente invention a pour objet un Système de Relargage de Médicament Auto-Émulsifiant (SRMAE) à base de butylbenzènephtaléine, ainsi que la méthode de préparation et les applications dudit système. Ledit SRMAE est constitué, au titre de constituants principaux, de 1 à 65 % de butylbenzènephtaléine et de 10 à 65 % d~un émulsifiant. Ledit SRMAE peut être utilisé dans la fabrication de formes galéniques diverses, solides ou liquides (par exemple tablettes, capsules dures/molles, ou autres). Ledit SRMAE est susceptible de s'auto-émulsifier dans l~appareil gastro-intestinal, augmentant ainsi la surface de contact entre le médicament et ledit appareil gastro-intestinal, et améliorant de ce fait l~absorptivité du médicament.
Feng Xiaolong
Gao Yuqing
Guo Wenmin
Liu Zhentao
Shen Dongmin
Oyen Wiggs Green & Mutala Llp
Shijiazhuang Pharma. Group Zhongqi Pharmaceutical Technology (sh Ltd.
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