A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/22 (2006.01)
Patent
CA 2283198
This invention relates to the use of butyrate prodrugs derived from lactic acid for treating inflammatory bowel disease. The invention also relates to the use of those prodrugs for the treatment of a chemotherapy- induced mucocutaneous side effect in a patient. The invention further relates to the use of butyrate prodrugs for treating lung, colo-rectal or prostate cancer. And the invention also relates to the use of butyrate prodrugs to treat cystic fibrosis and to enhance the efficiency of gene therapy.
Cette invention se rapporte à l'utilisation de promédicaments à base de butyrate, dérivés de l'acide lactique, pour le traitement de maladies inflammatoires de l'intestin. Cette invention se rapporte également à l'utilisation de ces promédicaments pour le traitement d'effets secondaires cutanéomuqueux induits par une chimiothérapie chez un patient. Cette invention se rapporte également à l'utilisation de promédicaments à base de butyrate pour le traitement du cancer de la prostate, des poumons ou du cancer colo-rectal. Cette invention se rapporte en outre à l'utilisation de promédicaments à base de butyrate pour traiter la mucoviscidose et renforcer l'efficacité de la thérapie génique.
Li Biqin
Su Michael Shin-San
Tung Roger D.
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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