Butyrylcholinesterase inhibitors

Details Butyrylcholinesterase inhibitors Butyrylcholinesterase inhibitors

C - Chemistry, Metallurgy

07

F

C07F 9/12 (2006.01) A61K 31/661 (2006.01) A61K 31/664 (2006.01) A61P 25/28 (2006.01) C07F 9/24 (2006.01) C07F 9/40 (2006.01) C07F 9/46 (2006.01)

Patent

CA 2704145

Butyrylcholinesterase inhibitors, their formulation, and their use primarily in the treatment of neurodegenerative diseases. These inhibitors generally are phosphates, phosphonates, phosphinates, and phosphoramidates. These inhibitors can be incorporated in pharmaceutical compositions and administered to a patient in therapeutically effective amounts to treat neurodegen-erative diseases.

L'invention concerne des inhibiteurs de butyrylcholinestérase, leur préparation et leur utilisation, principalement dans le traitement des maladies neurodégénératives. Les inhibiteurs selon l'invention sont généralement des phosphates, des phosphonates, des phosphinates et des phosphoramidates. Ces inhibiteurs peuvent être incorporés dans des compositions pharmaceutiques et administrés à un patient dans des quantités thérapeutiquement efficaces afin de traiter une maladie neurodégénérative.

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