C-4''-substituted macrolide derivatives

Details C-4''-substituted macrolide derivatives C-4''-substituted macrolide derivatives

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2293397

This invention relates to compounds of formula (1) and to pharmaceutically acceptable salts thereof. The compounds of formula (1) are potent antibacterial agents that may be used to treat various bacterial infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula (1) and to methods of treating bacterial infections by administering the compounds of formula (1). The invention also relates to methods of preparing the compounds of formula (1) and to intermediates useful in such preparation.

La présente invention concerne des composés de la formule (1): et leurs sels pharmaceutiquement acceptables. Les composés de la formule (1) constituent de puissants agents antibactériens qui peuvent être utilisés pour traiter diverses infections bactériennes et les troubles liés à ces infections. L'invention se rapporte également à des compositions pharmaceutiques contenant les composés de la formule (1) et à des procédés permettant de traiter les infections bactériennes en administrant les composés de la formule (1). L'invention concerne enfin des procédés de préparation des composés de la formule (1) et des intermédiaires utilisés dans cette préparation.

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