C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
167/147, 260/628
C07C 401/00 (2006.01) A61K 31/59 (2006.01) C07C 35/32 (2006.01) C07D 261/02 (2006.01) C07D 317/20 (2006.01) C07D 317/26 (2006.01) C07D 317/28 (2006.01) C07F 7/18 (2006.01)
Patent
CA 1311501
RAN 4212/42 ABSTRACT Process for the preparation of calciferol derivatives having anti-proliferative and differentiation-inducing activity and having the formula Image I wherein R is hydrogen and the dotted line in the side chain is an optional additional C-C-bond, or R is methyl and the dotted line in the side chain is an additional C-C-bond, in the 25R or 25S epimeric form or as mixtures thereof, starting from corresponding indenone derivatives: novel compounds falling under formula I and novel intermediates in the preparation of the compounds of formula I.
473719
Baggiolini Enrico Guiseppe
Batcho Andrew David
Truitt Gary Arthur
Uskokovic Milan Radoje
Wovkulich Peter Michael
Baggiolini Enrico Guiseppe
Batcho Andrew David
Gowling Lafleur Henderson Llp
Hoffmann-La Roche Limited/hoffmann-La Roche Limitee
Truitt Gary Arthur
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