C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/09 (2006.01) A61K 31/66 (2006.01) A61K 49/00 (2006.01) A61K 49/08 (2006.01) A61P 39/04 (2006.01) C07F 9/117 (2006.01)
Patent
CA 2380766
The invention relates to the calcium complex of[[(4R)-4-[bis[(carboxy- .kappa.O)methyl]amino-.kappa.N]-6, 9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2- oxa-6, 9-diaza-1-phosphaundecan-11-ylic--acid-.kappa.N6,.kappa.N9,.kappa.011]1- oxidato(6-)]-, tetrahydrogen (MS-325) and its salts, pharmaceutical agents that contain these complexes for the production of agents for the reduction of effects that are caused by heavy metals as well as processes for their production.
L'invention concerne le complexe calcique de [[(4R)-4-[bis[(carboxy-.kappa.O)méthyl]amino-.kappa.N]-6,9-bis[(carboxy-.kappa.O)méthyl]-1-[(4,4-diphénylcyclohéxyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundécan-11-ylic-acide-.kappa.N6,.kappa.N9,.kappa.011]1-oxidato(6-)]-, tétrahydrogène (MS-325) . L'invention concerne également les sels de ce dernier, les agents pharmaceutiques renfermant ces complexes et permettant de produire des agents qui réduisent les effets provoqués par les métaux lourds et leurs processus de production.
Michl Gunter
Niedballa Ulrich
Platzek Johannes
Marks & Clerk
Schering Aktiengesellschaft
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