Camptothecins with a modified lactone ring

Details Camptothecins with a modified lactone ring Camptothecins with a modified lactone ring

C - Chemistry, Metallurgy

07

D

C07D 491/22 (2006.01) A61K 31/4745 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2706635

<see formula I and II> Compounds of formula (I) or (II) are described: where the groups are as defined in the description here below, the racemic mixtures, their individual enantiomers, their individual diastereoisomers, their mixtures, and their pharmaceutically acceptable salts. Said compounds are topoisomerase I inhibitors.

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