Carbamate-substituted pyrazolopyridines

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 471/04 (2006.01) A61K 31/506 (2006.01) A61K 45/06 (2006.01) A61P 9/02 (2006.01)

Patent

CA 2485143

The present invention relates to compounds which stimulate soluble guanylate cyclase, to the preparation thereof and to the use thereof as medicaments, in particular as medicaments for the treatment of cardiovascular disorders and/or sexual dysfunction.

Composés de formule (I) dans laquelle R?1 ¿représente -NR?3¿C(=O)OR?4¿, R?2¿ représente hydrogène ou NH¿2?, R?3¿ représente hydrogène ou alkyle (C¿1?-C¿4?), et R?4¿ représente alkyle (C¿1?-C¿6?), qui stimulent la guanylate cyclase soluble, préparation desdits composés et leur utilisation en tant que médicaments, en particulier pour traiter des maladies cardio-vasculaires et / ou des dysfonctionnements sexuels.

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