Carbapenem compounds, their preparation and use

Details Carbapenem compounds, their preparation and use Carbapenem compounds, their preparation and use

C - Chemistry, Metallurgy

07

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260/299, 260/277

C07D 487/04 (2006.01) C07D 477/20 (2006.01) C07F 7/18 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 1254562

ABSTRACT OF THE DISCLOSURE Compounds of formula (1): Image (I) (wherein R1 is carboxy, -CONR4R5, cyano or hydroxymethyl, and R2 and R3 are hydrogen, alkyl or substituted alkyl, R4 and R5 being hydrogen or a variety of groups) have good antibiotic activity and reduced renal toxicity.

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