Carboxamide-substituted benzimidazole derivatives, processes...

C - Chemistry – Metallurgy – 07 – D

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C07D 235/16 (2006.01) A61K 31/4184 (2006.01) A61P 11/06 (2006.01) A61P 17/00 (2006.01) A61P 19/02 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2390631

The invention relates to carboxamide-substituted benzimidazole derivatives of general formula (I) (see formula I) wherein the groups R1, R2, R3 and R4 may have the meanings given in the claims and in the specification, processes for preparing them and the use of carboxamide- substituted benzimidazole derivatives as pharmaceutical compositions, particularly as pharmaceutical compositions with a tryptase-inhibiting effect.

L'invention concerne des dérivés de benzimidazole substitués par carboxamide correspondant à la formule générale (I), dans laquelle les restes R<1>, R<2>, R<3> et R<4> peuvent avoir les significations données dans les revendications et dans la description, ainsi que leur procédé de production et leur utilisation comme médicaments, en particulier comme médicaments inhibiteurs de la tryptase.

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