Cell matrix stimulated cell attachment and hemidesmosome...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/02 (2006.01) A61K 35/12 (2006.01) A61L 27/00 (2006.01) A61L 27/22 (2006.01) A61L 27/34 (2006.01) A61L 27/38 (2006.01) A61L 27/60 (2006.01) A61L 29/08 (2006.01) A61L 31/10 (2006.01) C07K 14/705 (2006.01) C07K 14/78 (2006.01) C07K 16/18 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2159471

Particular extracellular matrix proteins are disclosed, together with methods of using those proteins, and shaped articles coated with those proteins, which stimulate cell attachment and hemidesmosome formation in cells grown thereon, endocrine cell precursors grown on the matrix, including fetal pancreatic islet cell precursors, maintain biological function and differentiation.

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