Cephalosporin compounds and the production thereof

C - Chemistry – Metallurgy – 07 – D

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260/101, 167/187

C07D 501/20 (2006.01) A61K 31/545 (2006.01) C07D 277/32 (2006.01)

Patent

CA 1272714

NEW CEPHALOSPORIN COMPOUNDS AND THE PRODUCTION THEREOF ABSTRACT OF THE DISCLOSURE A class of new cephalosporin compounds (syn-isomer) is now provided, which is useful as antibacterial agent and is represetned by the general formula (I) Image (I) wherein R1 is an amino group or a protected amino group R2 is a lower alkyl group, a carboxymethyl group or a protected carboxymethyl group? R3 is a hydrogen atom, a salt-forming cation or a carboxyl-protecting group; A is an unsubstituted or substituted phenyl group, an unsub- stituted or substituted furyl group, an unsubstituted or substituted thiazolyl group or an unsubstituted or sub- stituted 3-lower-alkylthiazolio group, and a pharmaceutical- ly acceptable salt or ester thereof.

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