Cephalosporins, processes for their preparation and...

Details Cephalosporins, processes for their preparation and... Cephalosporins, processes for their preparation and...

C - Chemistry, Metallurgy

07

D

260/102, 260/104

C07D 501/20 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01) C07D 501/06 (2006.01) C07D 501/22 (2006.01) C07D 501/24 (2006.01) C07D 501/34 (2006.01) C07D 501/36 (2006.01) C07D 501/46 (2006.01) C07D 501/56 (2006.01) C07D 501/57 (2006.01)

Patent

CA 1164860

ABSTRACT Cephalosporins of the formula Image (I) wherein Y is hydrogen or methoxy, A is optionally substitut- ed aminothiazolyl, phenyl, 4-hydroxyphenyl, 3,4-dihydroxy- phenyl or thienyl; D is hydrogen, acetoxy, aminocarbonyloxy, pyridinium, aminocarbonylpyridinium, substituted triazin-3- ylthio or 1-substituted-tetrazol-5-ylthio; and R2 is optionally substituted heterocyclyl or heterocyclylmethyl; and E is hydrogen or a protecting group; as well as tautomers and salts thereof. The novel compounds may be prepared by a variety of processes, and formed into pharmaceutical compositions. The compounds possess anti- bacterial activity.

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