Cephem compounds, and their pharmaceutical compositions

Details Cephem compounds, and their pharmaceutical compositions Cephem compounds, and their pharmaceutical compositions

C - Chemistry, Metallurgy

07

D

C07D 501/24 (2006.01) A61K 31/545 (2006.01) A61K 31/695 (2006.01) C07D 501/00 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2147609

New cephem compounds of formula (I), wherein R1 is amino or protected amino, R2 is hydrogen, a hydroxy protective group, lower alkyl or mono(or di or tri)halo(lower)alkyl, R3 is carboxy or protected carboxy, and R4 is pyridylvinyl which may have suitable substituent(s), with proviso that (i) when R2 is hydrogen and R4 is 3-pyridylvinyl, then R3 is not carboxy, and (ii) when R2 is tetrahydropyranyl and R4 is 3-pyridylvinyl, then R3 is not benzhydryloxycarbonyl, and pharmaceutical acceptable salts thereof which are useful as a medicament.

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