Chemical compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/38 (2006.01) A61K 31/425 (2006.01) A61K 31/433 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) A61P 37/00 (2006.01) C07D 261/08 (2006.01) C07D 271/10 (2006.01) C07D 277/28 (2006.01) C07D 285/12 (2006.01) C07D 417/12 (2006.01) C07F 9/6539 (2006.01)

Patent

CA 2659473

The invention provides compounds formula I, their preparation, and their use as pharmaceutically active immunosuppressive agents for the treatment of autoimmune disorders, organ transplant rejection, disorders associated with an activated immune system, as well as other disorders modulated by lymphopenia or SlP receptors.

L'invention concerne des composés représentés par la formule I, leur préparation et leur utilisation comme agents immunosuppresseurs actifs d'un point de vue pharmaceutique pour le traitement de troubles auto-immuns, le rejet de greffon d'organe, les troubles associés à un système immunitaire activé, ainsi que d'autres troubles modulés par la lymphopénie ou les récepteurs S1P.

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